Male birth control slowing down sperm

A new study published today in the journal PLOS ONE details how a compound called EP binds to sperm proteins to significantly slow the overall mobility of the sperm without affecting hormones, making EP a potential "male pill" without side effects. Currently, condoms and surgical vasectomy are the only safe forms of birth control currently available for men. There are hormonal drugs in clinical trials that target the production of sperm, but these affect the natural hormones in men much like female contraceptives affect hormones in women. Further, no physical side effects were observed. O'Rand and Zelinski indicate that more work is needed before EP becomes available for human use.
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Male pill - why are we still waiting?

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This story is part of a week-long series on reproduction , from prenatal testing to childfree Reddit. On a recent morning in Los Angeles, Michael Medrano dabbed a teaspoon-sized glob of cold gel onto his shoulders. Massaged into his skin, it functions as the only birth control he and his wife, Julia, will use for the next year and a half. So when Medrano came across a post on Reddit recruiting participants for a clinical trial of this new kind of male contraceptive , it seemed worth a shot. Recently, some other couples in nine cities worldwide have similarly worked the gel into their daily routines. It is one of the largest investigations into hormonal male contraception ever. If the gel makes it to market, it will become the first hormonal contraceptive for men—more than a half-century after the first birth control pill was approved for women.
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The pill for men

We use cookies and other tracking technologies to improve your browsing experience on our site, show personalized content and targeted ads, analyze site traffic, and understand where our audiences come from. To learn more or opt-out, read our Cookie Policy. A pill, a gel, and a nonsurgical vasectomy are making their way through clinical trials. These choices are far from ideal. Condoms can be cumbersome, vasectomies require more surgery to reverse, and pulling out is, well, not exactly a reliable form of birth control.
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Every couple of months, starting in , clinicians injected dozens of men across eight countries with a serum containing the hormones progestin and testosterone. The men then had unprotected sex with their female partners, as part of a male-birth-control trial orchestrated by Conrad, a Virginia-based nonprofit devoted to reproductive-health research. Three years into the trial, things appeared to be going well: just four women had gotten pregnant. There was one big catch, however.
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